Contemporary neurotrophic factor research: towards a more human paradigm
Dimiter T. Tomov ( Bulgaria )
The nerve growth factor (NGF) has been discovered by Rita Levi-Montalcini in the early 1950’s (1,2). This paradigmic cell growth factor has gradually attracted the attention of many investigators from all over the world. In the very beginning, experimental research prevailed taking into consideration the still rather fundamental approach to the possible role of NGF and the subsequently discovered other neurotrophic factors in the living organism. Later on, an increasingly stable orienta tion of the scientific community towards the human beings, including a more outlined clinical research policy, has been emerging.
BiomedRev 1999; 10:107-110.
Received 10 October 1999 and accepted 23 November 1999.
Corespondence and reprint requests to Dr Dimiter T. Tomov, The Library and Information Service, Medical University, BG-9002 Varna, Bulgaria. Tel: 359 52 212 61, Fax: 359 52 222 584