Morphological transformation of sensory ganglion neurons and satellite cells
Seiji Matsuda, Naoto Kobayashi, Hiroyuki Wakisaka, Shouichiro Saito, Kyouko Saito, Kyojy Miyawaki, Katsumi Mominoki, Kazuhiro Shigemoto, Shingo Murakami, and Takashi Fujiwara (Japan)
The development of sensory ganglion neurons and satellite cells examined by scanning electron microscopy after removal of the connective tissue is reviewed. Sensory neurons are bipolar at early stages of development and later became pseudounipolar. This maturation event starts earlier but proceeds more slowly in chick than in rat embryos. These may due to the difference in the extent and intimacy of satellite cell investments between these two animal species. The neuronal perikaryal projections are observed by scanning electron microscopy after removal of the connective tissue and satellite cells. The morphometric analysis reveals that perikaryal projections are more numerous on the surface of mature pseudounipolar neurons than on that of premature bipolar neurons; they increase in number as the neuronal cell bodies grow larger. This may support the hypothesis that perikaryal projections are structural devices for increasing the neuron-satellite interface and for improving the efficiency of metabolic exchange between these two cell types.The important role of satellite cells in neuronal maturation is discussed.
Biomed Rev 2000; 11: 39-52.
—————————————————————————————-Received 5 January 2000 and accepted 28 May 2000.
Correspondence and reprint requests to Dr Seiji Matsuda, Department of Anatomy, Ehime University School of Medicine, Shigenobu, Ehime 791-02, Japan. Tel.: 81 89 960 5230, Fax: 81 89 960 5233,
E-mail: matsuda@m.ehime-u.ac.jp
