Methicillin resistant staphylococci: mechanisms of resistance
Katia K. Toshkova
Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen causing severe morbidity and mortality in many hospitals in Europe, in the United States andworldwide(l). Once these organisms are introduced into an institution they are particular difficult to eradicate (2). Colonization with MRSA is a majorproblemsince 30%-60% of patients who become colonized eventually develop infection (2), and these patients serve as reservoir for further nosocomial spread (3-12).
Biomed Rev 1994; 3: 65-71.