Sexual differentiation of the human brain

Sexual differentiation of the human brain
Dick F. Swaab, Jiang-Ningg Zhou, Mariann Fodor, and Michel A. Hofman (The Netherlands )

Sex differences in the structures of human hypot halamus and adjacent brain structures have been observed that seem to be related to gender, to gender problems such as transsexuality, and to sexual orientation, that is, heterosexual! ty and homosexuality. A Ithough these observations have yet to be confirmed, and their exact functional implications are far from clear, they open up a whole new field of structural-functional relationships in human brain research.
Biomed Rev 1997; 7:17-32
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Received for publication 5 April 1997 and accepted 17 Ju ly 1997

Correspondence and reprint requests to Dr Dick F. Swaab. Graduate School Neurosciences Amsterdam, Netherlands Institute for Brain Research, Meibergdreef 33, NL-1105 AZ Amsterdam, The Netherlands. Tel: 31 (20) 566 5500, Fax: 31 (20) 696 1006

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