NEUROBIOLOGY OF ADIPOSE TISSUE
Gorana Ranĉiĉ1, Mariyana G. Hristova2, and Vladmila Bojanic3
1Department of Embryology and Histology, Medical Faculty, University of Niš, Niš, Serbia, 2Division of Cell Biology, Medical University, Varna, Bulgaria, and
3Department of Pathophysiology, Medical Faculty, University of Niš, Niš, Serbia
Adipose tissue’s secretory phenotype paradigm shift has been upregulating since December 1, 1994, the birthday of leptin, an endocrine signaling protein (adipokine), which triggered the development of adipoendocrinology. Today, more than hundred adipokines are identified. Here an update of adipose-derived neurotrophic factors and neuropeptides and their receptors is presented, raising a hypothesis of neuroendocrine potential of this dynamic tissue.
Biomed Rev 2008; 19: 45-48.
Key words: adipose tissue, neurotrophins, neuropeptides
Received 22 November 2008, accepted 15 December 2008.
Correspondence and reprint request to Dr Gorana Ranĉiĉ, Department of Embryology and Histology, Medical Faculty, University of Niš, Niš, Serbia.
Tel.: 38 11853 5955,