ABO GENETIC SYSTEM, SEXUALLY TRANSMITTED INFECTIONS AND ADNDROGEN-ASSOCIATED DERMATOSES

ABO GENETIC SYSTEM, SEXUALLY TRANSMITTED INFECTIONS AND ADNDROGEN-ASSOCIATED DERMATOSES

Simeon Radev1, Ilko Bakardzhiev2, Diliana Panova3, and Vladimir Michev4
1Clinic of Dermatology, Naval Hospital, Varna, Bulgaria,
2University Medical College, Varna, Bulgaria,
3Piedmont Hospital, Atlanta, GA, USA, and
4Clinic of Dermatology, Military Medical Academy, Sofia,
Bulgaria

In the middle of 20th century, it was proved that ABO genetic system was the result of play of selection, including the infectious mortality due to two deadly epidemic collisions in the antiquity and with the main scene being Asian societies. It was discovered that plague tended to kill blood group O while smallpox blood group A carriers. Onwards no link was sought between this evolutionary phenomenon and blood group-related sexually transmitted infections and recurrent androgen-associated dermatoses (such as pityriasis versicolor and acne vulgaris) as well as sexual and fertility activity. Here we Dance Round such possible links. We found that these are expressed more strongly by blood group B carriers, and an attempt at translation of some relationships into population (intercontinental) level. We emphasize the genesis of blood group-related population gene pool equilibrium level and its attributes such as complex defense responses and co-operated immune reactions.
Biomed Rev 2011; 22: 77-80.

Key words: ABO genetic system, cell-mediated immunity, population gene pool, sexually transmitted infections, recurrent


Received 2 December 2011, revised 18 December 2011, accepted 23 December 2011.
Correspondence: Simeon G. Radev, MD, PhD, Consulting Dermatomycologist, Clinic of Dermatology, Naval Hospital, 3 Hristo Smirnenski Street, BG-9010 Varna, Bulgaria.
E-mail: simoesradeff@yahoo.co.uk
androgen-related dermatoses

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